Mac only: iKey is an automation application that promises to make painful, repetitive tasks a thing of the past. It's kind of like a less complicated version of Apple's Automator. Great for those simple things we do every day.
Say you open Safari each day and go to the same 8 websites and then copy some text which you email to someone. Instead of performing this same task each day for 15 mins with typing and clicking and opening and closing applications do it with iKey via one hotkey or menu item and let it work in the background while you do some other work or have a cup of tea. Seriously, why sacrifice your life to monotonous repetitive actions when your computer can do them for you.
iKey is 30 bucks but offers a free trial download. For Mac OS X 10.2 or higher